Calmodulin functions as an activator of Pur α binding to single-stranded purine rich DNA elements (PUR elements)
نویسندگان
چکیده
منابع مشابه
Structure/Function Analysis of Mouse Pur , a Single-stranded DNA-binding Repressor of Vascular Smooth Muscle -Actin Gene Transcription*
Plasticity of smooth muscle -actin gene expression in fibroblasts and vascular smooth muscle cells is mediated by opposing effects of transcriptional activators and repressors. Among these factors, three singlestranded DNA-binding proteins, Pur , Pur , and MSY1, have been implicated as coregulators of a cryptic 5 enhancer module. In this study, a molecular analysis of Pur , the least well chara...
متن کاملA eukaryotic SWI2/SNF2 domain, an exquisite detector of double-stranded to single-stranded DNA transition elements.
Many members of the SWI2/SNF2 family of adenosine triphosphatases participate in the assembly/disassembly of multiprotein complexes involved in the DNA metabolic processes of transcription, recombination, repair, and chromatin remodeling. The DNA molecule serves as an essential effector or catalyst for most of the members of this particular class of proteins, and the structure of the DNA may be...
متن کاملBinding of the dimeric Deinococcus radiodurans single-stranded DNA binding protein to single-stranded DNA.
Deinococcus radiodurans single-stranded (ss) DNA binding protein (DrSSB) originates from a radiation-resistant bacterium and participates in DNA recombination, replication, and repair. Although it functions as a homodimer, it contains four DNA binding domains (OB-folds) and thus is structurally similar to the Escherichia coli SSB (EcoSSB) homotetramer. We examined the equilibrium binding of DrS...
متن کاملEmission of Isocyanates from Pur-adhesives. Time Course of Emission from Curing Pur-adhesive
The time course of isocyanate emission from curing PUR-adhesives was studied in an emission test chamber. The adhesives under investigation were commercial products for fixing of textile floor coverings and based on methylene bisphenyl diisocyanate (MDI). Influence of the curing mechanism was studied by comparing the emission curves of one-component adhesive (OCA) and two-component adhesive (TC...
متن کاملFluorescent single-stranded DNA-binding protein from Plasmodium falciparum as a biosensor for single-stranded DNA
Single-stranded DNA (ssDNA) is a product of many cellular processes that involve double-stranded DNA, for example during DNA replication and repair, and is formed transiently in many others. Measurement of ssDNA formation is fundamental for understanding many such processes. The availability of a fluorescent biosensor for the determination of single-stranded DNA provides an important route to a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1999
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)34295-7